vialroom

#storage-coldchain 2026-03-19

Thursday17 messages5 participantstimes are UTC
Highlights from this day
  • swirl_not_shake — does the fridge in a hotel room count as a fridge 15:37
  • tyne_tracks — hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 17:08
  • lot_number_lou — how long is reconstituted actually good for at room temperature 17:13
TT

how cold is too cold, can it actually freeze in a normal fridge

VI

i log the fridge temperature daily and the room has never let me forget it

TT

hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct

SN

i would bin it

ConditionLyophilisedReconstituted
2-8 °Cfine, long termfine, weeks
Room temp, daysfine in every report herereported fine, shorter
Room temp, weeksreported finedo not
Warm transit, 30 °C+no failure loggedone visible degradant peak
Frozen oncefinecontested, no consensus
Freeze-thaw cycledfinethe room says no

gel packs

LN

how long is reconstituted actually good for at room temperature

mon  4.1 / door 7.2
tue  4.0 / door 7.8
wed  4.2 / door 6.9
thu  3.9 / door 7.4
fri  4.1 / door 8.1   <- shopping day
sat  4.3 / door 7.0
sun  4.0 / door 6.8
LN

update on the earlier thing what temperature does a domestic fridge door actually swing to

do i need to worry about light exposure or is that overthinking

SN

follow up i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

SN

the vial that visibly changed after a warm transit was the one that had already been reconstituted

SB

reconstituted solution is the fragile part. that is where the cold chain actually earns its keep