power cut for 7 hours, fridge stayed shut, am i fine
[edited]#storage-coldchain 2026-03-12
Thursday47 messages10 participantstimes are UTC
Highlights from this day
- private_script_pri — freeze thaw cycling is the risk, not one freeze. that is my read of it anyway 22:28
- net_peptide — anyone had a vial visibly change after a warm transit 22:46
- thirty_one_g — sorry to jump in buy a thermometer. mine reads 7.4 on the door and two degrees lower at the back 22:50
- fridge_six_two — the door swings four or five degrees every time somebody opens it. the back barely moves 23:31
unrelated but anyone tested a vial before and after a bad transit
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8if you are worried after a bad transit, test it. that is what the testing channels are for
a cooler with two gel packs held under eight degrees for eleven hours on a drive, anyway
solution is not
thats fine
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freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8gel packs
weights-monthly.csv
825 rows · not retained in the public archive
how long is reconstituted actually good for at room temperature
two to eight degrees. most domestic fridge doors are not in that range and people do not check
do you log the fridge temperature or is that too far
a liquid cold pack tells you it was above freezing, not that your vial cooked
sorry to jump in a few hours at room temperature is almost certainly nothing. a week is a different conversation, thats just me
not the door
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8update from 24 months ago: replaced the fridge, temperature is stable, no more anxiety, ymmv
not the freezer
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freeze debate again
anyone had a vial visibly change after a warm transit
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for flying, hand luggage every time. the hold is not temperature controlled the way people assume
sorry to jump in buy a thermometer. mine reads 7.4 on the door and two degrees lower at the back
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do i need to worry about light exposure or is that overthinking
i would bin it
the vial that visibly changed after a warm transit was the one that had already been reconstituted
transit-times.csv
326 rows · not retained in the public archive
my fridge is running at 6.2, is that out of range
light exposure matters much less than temperature for these. i still keep them in the carton
[edited]powder is robust
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8best travel setup for 6 days away with vials
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freezing reconstituted peptide is the one thing this channel has never agreed on, i could be wrong
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how cold is too cold, can it actually freeze in a normal fridge
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
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i would use it
i log the fridge temperature daily and the room has never let me forget it
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine, ymmv
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
vial-d-0718-front.png
900 × 1200 · 245 KB · not retained in the public archive
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
Testing queue: 7 submissions open, 79 awaiting dispatch.
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct, from memory
the door swings four or five degrees every time somebody opens it. the back barely moves
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reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
two to eight
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
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log it
i left it out overnight by accident, bin it or use it
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i keep everything at the back of the middle shelf, never the door, ask me again in a month
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quick one test it