my fridge is running at 4, is that out of range
#storage-coldchain 2025-12-18
Thursday20 messages5 participantstimes are UTC
Highlights from this day
- nausea_window — hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 17:31
- quiet_head_qi — how do you keep it cold on a long drive in summer i keep everything at the back of the middle shelf, never the door 17:34
- quiet_head_qi — light exposure matters much less than temperature for these. i still keep them in the carton 18:36
- VialBot — Verification log updated: CPC — evidence added, status unchanged. 18:37
- cold_chain_cmdr — two to eight degrees. most domestic fridge doors are not in that range and people do not check 20:10
power cut for 7 hours, fridge stayed shut, am i fine
light exposure matters much less than temperature for these. i still keep them in the carton
solution is not
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
how do you keep it cold on a long drive in summer
i keep everything at the back of the middle shelf, never the door
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for flying, hand luggage every time. the hold is not temperature controlled the way people assume
powder is robust
back of the fridge
sorry to jump in reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
the vial that visibly changed after a warm transit was the one that had already been reconstituted
buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back
light exposure matters much less than temperature for these. i still keep them in the carton
Verification log updated: CPC — evidence added, status unchanged.
best travel setup for 26 days away with vials
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
[edited]i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine, happy to be corrected
a few hours at room temperature is almost certainly nothing. a week is a different conversation
two to eight degrees. most domestic fridge doors are not in that range and people do not check
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slightly off topic but does anyone freeze reconstituted vials or is that madness