i left it out overnight by accident, bin it or use it
#storage-coldchain 2025-11-26
Wednesday40 messages11 participantstimes are UTC
Highlights from this day
- chain_of_custody — a cooler with two gel packs held under eight degrees for eleven hours on a drive, from memory freezing reconstituted peptide is the one thing this channel has never… 12:49
- fridge_thermo — the vial that visibly changed after a warm transit was the one that had already been reconstituted 13:04
- one_data_point — i keep everything at the back of the middle shelf, never the door, we shall see 13:09
hand luggage
do you keep the unopened vials and the in-use one in the same place
coming back to this if you are worried after a bad transit, test it. that is what the testing channels are for, anyway
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light exposure matters much less than temperature for these. i still keep them in the carton
a cooler with two gel packs held under eight degrees for eleven hours on a drive, from memory
freezing reconstituted peptide is the one thing this channel has never agreed on
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how cold is too cold, can it actually freeze in a normal fridge
update from 12 months ago: replaced the fridge, temperature is stable, no more anxiety
freeze debate again
the vial that visibly changed after a warm transit was the one that had already been reconstituted
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
log it
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
i keep everything at the back of the middle shelf, never the door, we shall see
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buy a thermometer
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i would bin it
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
follow up a few hours at room temperature is almost certainly nothing. a week is a different conversation, ymmv
freezing reconstituted peptide is the one thing this channel has never agreed on
the door swings four or five degrees every time somebody opens it. the back barely moves
i would use it
solution is not
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coming back to this for flying, hand luggage every time. the hold is not temperature controlled the way people assume
back of the fridge
Digest for the week of 2025-01-01 has been published.
coming back to this coming back after 14 months, is the pinned storage table still current
a cooler with two gel packs held under eight degrees for eleven hours on a drive
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
coming back to this two to eight degrees. most domestic fridge doors are not in that range and people do not check
ok so the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
does anyone freeze reconstituted vials or is that madness
buy a thermometer. mine reads 4.8 on the door and two degrees lower at the back
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
i log the fridge temperature daily and the room has never let me forget it
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best travel setup for 12 days away with vials
door shelf or back of the fridge
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thats fine
test it
a liquid cold pack tells you it was above freezing, not that your vial cooked
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear, your mileage will differ
cold pack arrived completely liquid, does that mean anything