the door swings four or five degrees every time somebody opens it. the back barely moves
#storage-coldchain 2025-11-14
Friday41 messages7 participantstimes are UTC
Highlights from this day
- blank_run — aliquoting is the important half of that sentence. it is the freeze-thaw cycling that does damage, not being frozen 15:39
- blank_run — every cycle concentrates solutes at the ice front and shoves peptide onto interfaces. once, maybe. six times, no 15:42
- blank_run — yes. a frozen gel pack against glass will freeze your vial and then you are back in the freeze argument by accident 16:21
- blank_run — the thermometer with a min/max readout is the one to own. it tells you afterwards how bad it actually got 17:30
- nordic_price_nils — peaked at 12C for a couple of hours by the readout. used the vial, nothing was different 17:32
anyone tested a vial before and after a bad transit
🧪1😂6
test it
14:12ferrous_ash pinned a message to this channel
thats fine
📈14⚠️2
log it
📉10🧊10🧪4
i would use it
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
[edited]powder is robust
gel packs
buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back
i log the fridge temperature daily and the room has never let me forget it
settle this. can you freeze reconstituted peptide
you can. whether you should is where the room splits
i freeze in single-dose aliquots and have done for two years
aliquoting is the important half of that sentence. it is the freeze-thaw cycling that does damage, not being frozen
every cycle concentrates solutes at the ice front and shoves peptide onto interfaces. once, maybe. six times, no
so never refreeze
never refreeze
✅10
the other problem is you cannot see the damage. it looks identical thawed
which is why i just do not freeze. i mix smaller volumes more often instead
that is the boring correct answer, is it not
usually is. the fridge is a solved problem and the freezer is an experiment
what about travel
my list, three flights so far
- powder vials in the original box, inside a soft cooler
- two gel packs frozen solid at departure, wrapped in a tea towel
- vial NOT touching the gel pack (frozen pack + glass = frozen vial)
- syringes in a clear bag, with the pharmacy label if you have one
- a letter from the prescriber if it is a prescribed pen
- a min/max thermometer in the cooler so you know what happened📌8✈️4
the not-touching thing catches people out
yes. a frozen gel pack against glass will freeze your vial and then you are back in the freeze argument by accident
tea towel, sock, anything
carry on or checked
carry on, always. hold luggage temperature is a lottery
and hold luggage gets lost, which is worse than warm
makes sense
power cut question — mine was out nine hours last month
closed fridge, nine hours, cool house? it will have drifted up but not far
the failure mode is opening it every twenty minutes to check
i did exactly that
😅7
everyone does
the thermometer with a min/max readout is the one to own. it tells you afterwards how bad it actually got
peaked at 12C for a couple of hours by the readout. used the vial, nothing was different
logged. those anecdotes are all we have in this channel
and better than nothing