vialroom

#storage-coldchain 2025-10-11

Saturday51 messages11 participantstimes are UTC
Highlights from this day
  • protein_floor — the door swings four or five degrees every time somebody opens it. the back barely moves, i could be wrong 06:19
  • protein_floor — for flying, hand luggage every time. the hold is not temperature controlled the way people assume, your mileage will differ 07:13
  • rotterdam_recon — i log the fridge temperature daily and the room has never let me forget it 10:00
  • back_from_away — how cold is too cold, can it actually freeze in a normal fridge 10:31
  • factory_direct_fi — update from 22 months ago: replaced the fridge, temperature is stable, no more anxiety 10:58
PF

the door swings four or five degrees every time somebody opens it. the back barely moves, i could be wrong

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if you are worried after a bad transit, test it. that is what the testing channels are for

EE

freeze thaw cycling is the risk, not one freeze. that is my read of it anyway, i could be wrong

EE

two to eight degrees. most domestic fridge doors are not in that range and people do not check

i keep everything at the back of the middle shelf, never the door

NN

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it, not advice obviously

[edited]
PF

the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in

PF

for flying, hand luggage every time. the hold is not temperature controlled the way people assume, your mileage will differ

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BF

nobody here can tell you a vial is safe. we can tell you what has and has not survived for us

log it

freeze debate again

[edited]

thats fine

anyone tested a vial before and after a bad transit

EE

do you keep the unopened vials and the in-use one in the same place
i log the fridge temperature daily and the room has never let me forget it

RR

a few hours at room temperature is almost certainly nothing. a week is a different conversation

RR

i log the fridge temperature daily and the room has never let me forget it

📈1😂11

the vial that visibly changed after a warm transit was the one that had already been reconstituted

lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear

does anyone freeze reconstituted vials or is that madness

hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct

RR

while im here lyophilised at room temp for 17 days in transit, worried or not
i keep everything at the back of the middle shelf, never the door

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BF

how cold is too cold, can it actually freeze in a normal fridge

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VB

Purity check: no report on file for lot C-4402. Nothing logged either way.

FD

while im here reconstituted solution is the fragile part. that is where the cold chain actually earns its keep

FD

update from 22 months ago: replaced the fridge, temperature is stable, no more anxiety

mon  4.1 / door 7.2
tue  4.0 / door 7.8
wed  4.2 / door 6.9
thu  3.9 / door 7.4
fri  4.1 / door 8.1   <- shopping day
sat  4.3 / door 7.0
sun  4.0 / door 6.8
HM

freezing reconstituted peptide is the one thing this channel has never agreed on

HM

i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why

buy a thermometer. mine reads 4 on the door and two degrees lower at the back

my fridge is running at 4.8, is that out of range

solution is not

two to eight

for the archive not the door

EE

a cooler with two gel packs held under eight degrees for eleven hours on a drive, take that with a pinch of salt