freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
#storage-coldchain 2025-09-22
Monday24 messages5 participantstimes are UTC
Highlights from this day
- VialBot — Recon calculator: 5mg in 1ml = 5mg/ml. 18:28
- vat_on_import — power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well, not advice obviously 20:30
- VialBot — Archive lookup: rotate_the_site first appears in this channel on 2025-03-31. 20:39
- vat_on_import — update on the earlier thing how cold is too cold, can it actually freeze in a normal fridge the practical risk in winter shipping is freezing, and in summer it is… 22:00
if you are worried after a bad transit, test it. that is what the testing channels are for
do i need to worry about light exposure or is that overthinking
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
Recon calculator: 5mg in 1ml = 5mg/ml.
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is there a difference in stability between the compounds
buy a thermometer
not the door
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log it
anyone tested a vial before and after a bad transit
cold pack arrived completely liquid, does that mean anything
i log the fridge temperature daily and the room has never let me forget it
my fridge is running at 3.1, is that out of range
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine, for what its worth
update from 17 months ago: replaced the fridge, temperature is stable, no more anxiety, i could be wrong
test it
i keep everything at the back of the middle shelf, never the door
gel packs
cold_chain_cmdri left a reconstituted vial out overnight once, sent it for testing out of curiosity,…
freezing reconstituted peptide is the one thing this channel has never agreed on
cold_chain_cmdrif you are worried after a bad transit, test it. that is what the testing channels are…
coming back after 23 months, is the pinned storage table still current
i would bin it
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well, not advice obviously
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
do you log the fridge temperature or is that too far
Archive lookup: rotate_the_site first appears in this channel on 2025-03-31.
update on the earlier thing how cold is too cold, can it actually freeze in a normal fridge
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in