for flying, hand luggage every time. the hold is not temperature controlled the way people assume
#storage-coldchain 2025-08-24
- endotoxin_ed — power cut for 2 hours, fridge stayed shut, am i fine 11:57
- two_eight_c — i log the fridge temperature daily and the room has never let me forget it 11:58
- endotoxin_ed — is a five pound fridge thermometer actually worth it 12:23
- two_eight_c — unopened and in-use in the same place is fine. just keep the in-use one where you can reach it, ill dig out the number 15:26
coming back to this how cold is too cold, can it actually freeze in a normal fridge
anyone tested a vial before and after a bad transit
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
hand luggage
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
the door swings four or five degrees every time somebody opens it. the back barely moves
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
freezing reconstituted peptide is the one thing this channel has never agreed on
a few hours at room temperature is almost certainly nothing. a week is a different conversation
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
i keep everything at the back of the middle shelf, never the door
if you are worried after a bad transit, test it. that is what the testing channels are for
ok so the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
freeze debate again
power cut for 2 hours, fridge stayed shut, am i fine
i log the fridge temperature daily and the room has never let me forget it
two to eight
light exposure matters much less than temperature for these. i still keep them in the carton
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
is a five pound fridge thermometer actually worth it
*Medutest not the other one
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
update from 22 months ago: replaced the fridge, temperature is stable, no more anxiety
buy a thermometer. mine reads 7.4 on the door and two degrees lower at the back
buy a thermometer
coming back to this lyophilised at room temp for 11 days in transit, worried or not
solution is not
two to eight degrees. most domestic fridge doors are not in that range and people do not check, someone check my working
back of the fridge
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine, ask me again in a month
door shelf or back of the fridge
i left it out overnight by accident, bin it or use it
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
a liquid cold pack tells you it was above freezing, not that your vial cooked
cold pack arrived completely liquid, does that mean anything
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it, ill dig out the number