i left it out overnight by accident, bin it or use it
#storage-coldchain 2025-07-06
Sunday35 messages7 participantstimes are UTC
Highlights from this day
- reta_resting_hr — i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why 09:47
- lyophile_liv — cold pack arrived completely liquid, does that mean anything 10:41
- VialBot — Assay note: HJ lot B-0329 reported at 98.6% of label content. 12:01
- septum_sal — door shelf or back of the fridge 12:43
- reta_resting_hr — the door swings four or five degrees every time somebody opens it. the back barely moves 13:21
buy a thermometer. mine reads 3.1 on the door and two degrees lower at the back
sorry to jump in for flying, hand luggage every time. the hold is not temperature controlled the way people assume, your mileage will differ
[edited]solution is not
does anyone freeze reconstituted vials or is that madness
test it
a few hours at room temperature is almost certainly nothing. a week is a different conversation
do i need to worry about light exposure or is that overthinking
do you keep the unopened vials and the in-use one in the same place
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
i log the fridge temperature daily and the room has never let me forget it
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
if you are worried after a bad transit, test it. that is what the testing channels are for, n of 1 obviously
i would use it
does the fridge in a hotel room count as a fridge
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
cold pack arrived completely liquid, does that mean anything
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gel packs
anyone had a vial visibly change after a warm transit
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
Assay note: HJ lot B-0329 reported at 98.6% of label content.
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sorry to jump in a cooler with two gel packs held under eight degrees for eleven hours on a drive
freezing reconstituted peptide is the one thing this channel has never agreed on
my fridge is running at 4.8, is that out of range
[edited]door shelf or back of the fridge
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8best travel setup for 12 days away with vials
i would bin it
hand luggage
the door swings four or five degrees every time somebody opens it. the back barely moves
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buy a thermometer
light exposure matters much less than temperature for these. i still keep them in the carton, still working it out
is there a difference in stability between the compounds