vialroom

#semaglutide 2026-06-02

Tuesday20 messages5 participantstimes are UTC
Highlights from this day
  • tansy_tests — sorry to jump in does anyone actually run a five week step instead of four 18:09
  • verify_or_dont — im 25 months in at 5 and the appetite effect faded, is that a thing 18:27
  • gradient_greg — dose day is sunday for me only because thats when i remember, not because sunday matters 18:42
TT

is the plateau usually appetite coming back or just the scale stopping

JJ

how long till steady state, ive read the half life is about a week

does the licensed ceiling for weight differ from the diabetes one

TT

held at 2.5 and lost 19lb over 13 months, slower than the trials and fine by me

*Medutest not the other one

TT

sorry to jump in does anyone actually run a five week step instead of four

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance
VO

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

VO

im 25 months in at 5 and the appetite effect faded, is that a thing

📈2💀11
GG

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution

GG

sorry to jump in my 30 vial in 2ml gives 8mg/ml so 10 lands on 30 units, thats why i picked that volume

dose day is sunday for me only because thats when i remember, not because sunday matters

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance

does moving my dose day by two days matter with a seven day half life

TT

i dont think the plateau is a dose problem most of the time, but i cant prove that

ok so licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose