vialroom

#semaglutide 2026-05-19

Tuesday29 messages8 participantstimes are UTC
Highlights from this day
  • mcg_not_mg — the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, happy to be corrected went 1 to 1.7 too fast and spent two weeks… 17:49
  • comment_fatigue — i held at 7.5 for 3 months and it was the best decision i made 18:48
  • comment_fatigue — was SELECT the one that ran to 68 weeks or am i mixing them up 19:17
  • comment_fatigue — vial units and pen clicks are different systems, mixing the two is how people end up wrong, thats just me 20:14
HL

steady state takes weeks

Trial scheduleWhat most people here do
Step interval4 weeks, fixed4-12 weeks, on symptoms
Holdingprotocol deviationnormal and expected
Top dosereached by designoften never reached
Coming downnot studiedcommon at maintenance
SI

does the licensed ceiling for weight differ from the diabetes one

SI

does moving my dose day by two days matter with a seven day half life

held there too

[edited]
MN

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, happy to be corrected
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

SV

slightly off topic but did anyone hold at 12 longer than four weeks before going up

MN

anyone gone from 10 straight to 2.4 or is that too big a jump

SV

what did SELECT actually measure, i see it quoted for everything

SV

my plateau was the scale stopping while appetite stayed suppressed, which is a different problem

CF

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

FD

$72 a month for compounded against what brand costs locally is why most people here use vials

i dont think the plateau is a dose problem most of the time, but i cant prove that

the plateau hit me at 5 weeks and moved again about a month later without a dose change

how did people handle the jump from 1 to 1.7

*Janoshik not the other one

dose day is sunday for me only because thats when i remember, not because sunday matters

MN

restarted after 17 months off at a low dose and the nausea arrived exactly like the first time

SI

is the plateau usually appetite coming back or just the scale stopping