vialroom

#semaglutide 2026-04-24

Friday19 messages3 participantstimes are UTC
Highlights from this day
  • juno_joins — went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down, for what its worth 16:29
  • mhra_unlicensed — whats the actual licensed ceiling, i keep seeing different numbers 16:51
  • mhra_unlicensed — is 2.4 the top or do people go past it 19:10
JJ

moving my dose day by a day or two never did anything noticeable for me

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down, for what its worth

half life is about a week so youre roughly four to five weeks to steady state on any new dose

slower worked better

MU

restarted after 10 months off at a low dose and the nausea arrived exactly like the first time

SELECT wasnt weight

steady state takes weeks

whats the actual licensed ceiling, i keep seeing different numbers

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

my dose day drifted from friday to sunday, does that reset anything

quick one STEP is several trials, so saying STEP said x is usually wrong without a number after it

JJ

quick one did anyone titrate slower than four weeks a step and how did that go

[edited]

9 months at 2.4 and the honest summary is diminishing returns after the first half

GB

compounded and brand felt the same to me at 15, which is one person and nothing more