thats STEP 1
#semaglutide 2026-04-21
Tuesday23 messages6 participantstimes are UTC
Highlights from this day
- hydrate_hana — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 16:39
- karl_fischer — went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step 17:31
- net_peptide — the plateau hit me at 24 weeks and moved again about a month later without a dose change 17:37
- blind_submit — half life is about a week so youre roughly four to five weeks to steady state on any new dose 18:00
- nettle_notes — going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 19:30
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
back after 23 months off, do i restart at 0.25 or somewhere higher
five week steps worked better for me than four, purely on how the second week felt
anyone gone from 0.5 straight to 5 or is that too big a jump
went too fast once
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
slower worked better
follow up im 6 months in at 0.5 and the appetite effect faded, is that a thing
did the STEP 4 withdrawal arm show what i think it showed
the plateau hit me at 24 weeks and moved again about a month later without a dose change
25 months at 2.4 and the honest summary is diminishing returns after the first half
plateaus move
half life is about a week so youre roughly four to five weeks to steady state on any new dose
was STEP 1 the one that ran to 68 weeks or am i mixing them up
mine faded too
the appetite effect faded for me around 18 months and going up fixed it for a while
steady state takes weeks
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
2.4 is the ceiling
held there too
im at 10 and stuck, did anyone break a plateau without going up
i held at 0.25 for 6 months and it was the best decision i made