vialroom

#semaglutide 2026-04-06

Monday17 messages6 participantstimes are UTC
Highlights from this day
  • cold_chain_cmdr — 23 months at 2.4 and the honest summary is diminishing returns after the first half went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and… 18:22
  • power_through_no — coming back to this changed my mind on the four week rule, i think it depends entirely on how the current dose feels, happy to be corrected 18:57
  • step_one_sian — if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule 19:32
  • power_through_no — my 10 vial in 2.5ml gives 10mg/ml so 12 lands on 5 units, thats why i picked that volume, still working it out 19:40
CC

update on the earlier thing i held at 1 for 5 months and it was the best decision i made

CC

23 months at 2.4 and the honest summary is diminishing returns after the first half
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

ZZ

lost about 35kg on the low doses before i even got to 1, which surprised me, i could be wrong

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

PT

vial units and pen clicks are different systems, mixing the two is how people end up wrong, happy to be corrected

PT

coming back to this changed my mind on the four week rule, i think it depends entirely on how the current dose feels, happy to be corrected

*PeptideMeter not the other one

FN

same dose day

Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes (STEP 2)
The Lancet · 2021
The type 2 diabetes population, where the weight response is generally smaller.
SO

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

site-rotation-map.png
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five week steps worked better for me than four, purely on how the second week felt

SO

the plateau hit me at 30 weeks and moved again about a month later without a dose change, we shall see

PT

my 10 vial in 2.5ml gives 10mg/ml so 12 lands on 5 units, thats why i picked that volume, still working it out

😂7❤️4