while im here half life is about a week so youre roughly four to five weeks to steady state on any new dose, i have it written down somewhere
[edited]🎉9⚠️2
#semaglutide 2026-03-02
Monday17 messages5 participantstimes are UTC
Highlights from this day
- knees_first — while im here half life is about a week so youre roughly four to five weeks to steady state on any new dose, i have it written down somewhere 08:09
- knees_first — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 09:51
- split_dose_sam — going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution 10:16
- knees_first — the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing 12:07
- knees_first — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not advice obviously 12:16
Inter-lab diff for lot E-2205: 99.4% vs 99.2%. Within expected range.
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
🎉11✅7⚠️3
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
🧊1❤️11📉1
for the archive $55 a month for compounded against what brand costs locally is why most people here use vials
im at 5 and stuck, did anyone break a plateau without going up
whats the actual licensed ceiling, i keep seeing different numbers
transit-times.csv
694 rows · not retained in the public archive
held there too
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
🤝3📉6🧪4
brand vs compounded, is there a difference people can actually feel
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
went too fast once
moving my dose day by a day or two never did anything noticeable for me, i have it written down somewhere
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not advice obviously
🧊7💀8❤️3
slower worked better
STEP is several trials, so saying STEP said x is usually wrong without a number after it
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing