vialroom

#semaglutide 2026-01-20

Tuesday17 messages4 participantstimes are UTC
Highlights from this day
  • step_one_sian — does the licensed ceiling for weight differ from the diabetes one 17:53
  • step_one_sian — if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule 17:57
  • bpc_sceptic — does the seven day half life mean the last two days are weaker held at 15 and lost 104lb over 13 months, slower than the trials and fine by me 18:30
  • bpc_sceptic — im 2 months in at 2 and the appetite effect faded, is that a thing 20:02

lost about 16kg on the low doses before i even got to 1, which surprised me

whats the actual licensed ceiling, i keep seeing different numbers

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

SO

does the licensed ceiling for weight differ from the diabetes one

⚠️16

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

⚠️1
BS

does the seven day half life mean the last two days are weaker
held at 15 and lost 104lb over 13 months, slower than the trials and fine by me

IS

the plateau hit me at 4 weeks and moved again about a month later without a dose change

BS

held at 12 and lost 23lb over 8 months, slower than the trials and fine by me

my dose day drifted from friday to sunday, does that reset anything

back after 18 months off, do i restart at 0.25 or somewhere higher

BS

went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down

how many weeks before you noticed anything at 1

my 15 vial in 1.5ml gives 8mg/ml so 2 lands on 40 units, thats why i picked that volume

update on the earlier thing STEP is several trials, so saying STEP said x is usually wrong without a number after it