coming back to this five week steps worked better for me than four, purely on how the second week felt
#semaglutide 2025-12-25
- vialkeeper — my plateau was the scale stopping while appetite stayed suppressed, which is a different problem went to 2.4 and the extra suppression wasnt worth the GI for me, so i… 06:42
- vialkeeper — does the seven day half life mean the last two days are weaker held at 2.5 and lost 9lb over 23 months, slower than the trials and fine by me 07:37
- vialkeeper — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 07:38
- sharps_comedy — slightly off topic but 24 months at 2.4 and the honest summary is diminishing returns after the first half 08:36
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
genuine question compounded and brand felt the same to me at 5, which is one person and nothing more
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
im at 5 and stuck, did anyone break a plateau without going up
seven days ish
does the seven day half life mean the last two days are weaker
held at 2.5 and lost 9lb over 23 months, slower than the trials and fine by me
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgSELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
[edited]how long did the first 12kg take for people at the low doses
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
how long till steady state, ive read the half life is about a week
slightly off topic but 24 months at 2.4 and the honest summary is diminishing returns after the first half
not the same trial
whats the actual licensed ceiling, i keep seeing different numbers
did anyone titrate slower than four weeks a step and how did that go
€55 a month for compounded against what brand costs locally is why most people here use vials, i could be wrong
brand vs compounded, is there a difference people can actually feel
slower worked better
quick one is the plateau usually appetite coming back or just the scale stopping
ok so lost about 35kg on the low doses before i even got to 1, which surprised me
*VendorInvestigate not the other one
vial units and pen clicks are different systems, mixing the two is how people end up wrong