is 2.4 the top or do people go past it
#semaglutide 2025-11-13
Thursday36 messages9 participantstimes are UTC
Highlights from this day
- shame_and_meds — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 12:25
- half_life_hal — did anyone hold at 2.5 longer than four weeks before going up 12:29
- perth_pin — my VendorInvestigate report on the WXT vial came back 96.8 against a certificate saying 97.4 13:46
- apnoea_down_two — compounded and brand felt the same to me at 2, which is one person and nothing more, still working it out 17:47
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping, still working it out
€94 a month for compounded against what brand costs locally is why most people here use vials
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
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the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
did anyone hold at 2.5 longer than four weeks before going up
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anyone compared their 4 vial dosing against the pen increments
five week steps worked better for me than four, purely on how the second week felt
the long half life flattens the trough more than people expect, i never felt a day seven dip
i held at 12 for 9 months and it was the best decision i made
the plateau hit me at 32 weeks and moved again about a month later without a dose change
im at 7.5 and stuck, did anyone break a plateau without going up
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whats the actual licensed ceiling, i keep seeing different numbers
my VendorInvestigate report on the WXT vial came back 96.8 against a certificate saying 97.4
dose day is sunday for me only because thats when i remember, not because sunday matters, n of 1 obviously
is the plateau usually appetite coming back or just the scale stopping
restarted after 20 months off at a low dose and the nausea arrived exactly like the first time, ask me again in a month
*VendorInvestigate not the other one
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
vial units and pen clicks are different systems, mixing the two is how people end up wrong
Reminder set. I will post here in 8 days.
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steady state takes weeks
did the STEP 4 withdrawal arm show what i think it showed
went too fast once
the appetite effect faded for me around 9 months and going up fixed it for a while
10 months at 2.4 and the honest summary is diminishing returns after the first half, i have it written down somewhere
give it four weeks
STEP is several trials, so saying STEP said x is usually wrong without a number after it
right so SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
how did people handle the jump from 1 to 1.7
does the seven day half life mean the last two days are weaker
lost about 23kg on the low doses before i even got to 1, which surprised me
does moving my dose day by two days matter with a seven day half life
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
compounded and brand felt the same to me at 2, which is one person and nothing more, still working it out
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