vialroom

#semaglutide 2025-10-22

Wednesday18 messages6 participantstimes are UTC
Highlights from this day
  • baseline_drift — vial units and pen clicks are different systems, mixing the two is how people end up wrong, anyway 11:18
  • VialBot — Batch lookup A-2601: 8 independent reports on file, earliest 2025-01-12. 12:57
  • gall_bladder_gav — dose day is sunday for me only because thats when i remember, not because sunday matters 13:15
  • VialBot — New independent result logged — KP, lot E-2205, purity 99% (Janoshik). 13:17
  • gall_bladder_gav — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 13:47
BD

i dont think the plateau is a dose problem most of the time, but i cant prove that

BD

vial units and pen clicks are different systems, mixing the two is how people end up wrong, anyway

im at 1.7 and stuck, did anyone break a plateau without going up

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

FT

slower worked better

Cited study
Tirzepatide versus Semaglutide Once Weekly in Type 2 Diabetes (SURPASS-2)
New England Journal of Medicine · 2021
The head-to-head everyone quotes. Note the semaglutide comparator dose.
FT

i stayed on 1.7 for 5 months and never went to 2.4, appetite was already where i needed it

VB

Batch lookup A-2601: 8 independent reports on file, earliest 2025-01-12.

BD

the long half life flattens the trough more than people expect, i never felt a day seven dip

moving my dose day by a day or two never did anything noticeable for me

GB

dose day is sunday for me only because thats when i remember, not because sunday matters

4💀3📈2
VB

New independent result logged — KP, lot E-2205, purity 99% (Janoshik).

GB

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

GB

held at 5 and lost 10lb over 12 months, slower than the trials and fine by me, i could be wrong