the long half life flattens the trough more than people expect, i never felt a day seven dip
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#semaglutide 2025-08-28
Thursday30 messages7 participantstimes are UTC
Highlights from this day
- VialBot — Digest for the week of 2025-02-11 has been published. 07:04
- ring_size_down — how long did the first 44kg take for people at the low doses 07:09
- taste_changed — sorry to jump in STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping, thats one data point 09:11
- taste_changed — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 09:13
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
[edited]Digest for the week of 2025-02-11 has been published.
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i dont think the plateau is a dose problem most of the time, but i cant prove that, i think
how long did the first 44kg take for people at the low doses
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five week steps worked better for me than four, purely on how the second week felt, we shall see
steady state takes weeks
how many weeks before you noticed anything at 2
compounded and brand felt the same to me at 2.5, which is one person and nothing more, ymmv
whats the actual licensed ceiling, i keep seeing different numbers
does anyone actually run a five week step instead of four
vial units and pen clicks are different systems, mixing the two is how people end up wrong
my Medutest report on the QYB vial came back 96.8 against a certificate saying 99, take that with a pinch of salt
did the STEP 4 withdrawal arm show what i think it showed
not the same trial
seven days ish
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
sorry to jump in STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping, thats one data point
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*sorry, HJ
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
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*week 15 not week 8
how did people handle the jump from 1 to 1.7
lost about 4kg on the low doses before i even got to 1, which surprised me
the plateau hit me at 7 weeks and moved again about a month later without a dose change
is the plateau usually appetite coming back or just the scale stopping
is there a reason to hold at 1.7 rather than going to 2.4
SELECT wasnt weight
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing, thats one data point
unrelated but is the plateau at 11 weeks normal or am i doing something wrong
while im here went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step