i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
#semaglutide 2025-08-03
Sunday42 messages8 participantstimes are UTC
Highlights from this day
- cagri_curious — compounded and brand felt the same to me at 0.25, which is one person and nothing more, anyway 16:51
- mg_per_ml — back after 10 months off, do i restart at 0.25 or somewhere higher 17:02
- lead_time_lars — did anybody find a difference between ERP and pharmacy at the same 15 18:07
- lead_time_lars — half life is about a week so youre roughly four to five weeks to steady state on any new dose 18:52
compounded and brand felt the same to me at 0.25, which is one person and nothing more, anyway
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my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
back after 10 months off, do i restart at 0.25 or somewhere higher
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update on the earlier thing does the licensed ceiling for weight differ from the diabetes one
is 2.4 the top or do people go past it
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, for what its worth
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went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
held there too
genuine question STEP 1 ran to 68 weeks. thats the one everyone half remembers
is the plateau usually appetite coming back or just the scale stopping
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, anyway
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going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution, thats just me
[edited]lost about 15kg on the low doses before i even got to 1, which surprised me
the long half life flattens the trough more than people expect, i never felt a day seven dip
restarted after 16 months off at a low dose and the nausea arrived exactly like the first time
vial units and pen clicks are different systems, mixing the two is how people end up wrong
did anybody find a difference between ERP and pharmacy at the same 15
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how many weeks before you noticed anything at 2.4
moving my dose day by a day or two never did anything noticeable for me
medutest-report-e-2205.pdf
3 pages · 699 KB · not retained in the public archive
vials not pens here
i dont think the plateau is a dose problem most of the time, but i cant prove that
coming back to this changed my mind on the four week rule, i think it depends entirely on how the current dose feels
*week 24 not week 9
the plateau hit me at 3 weeks and moved again about a month later without a dose change
£185 a month for compounded against what brand costs locally is why most people here use vials
half life is about a week so youre roughly four to five weeks to steady state on any new dose
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not the same trial, i could be wrong
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while im here i held at 10 for 8 months and it was the best decision i made
sorry to jump in anyone compared their 10 vial dosing against the pen increments
dose day is sunday for me only because thats when i remember, not because sunday matters
five week steps worked better for me than four, purely on how the second week felt
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FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
held at 2 and lost 86lb over 22 months, slower than the trials and fine by me
2.4 is the ceiling
give it four weeks
[edited]23 months at 2.4 and the honest summary is diminishing returns after the first half
im at 2.5 and stuck, did anyone break a plateau without going up
went too fast once
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same dose day
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping