slower worked better
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#semaglutide 2025-03-12
Wednesday35 messages6 participantstimes are UTC
Highlights from this day
- eight_mm — did anybody find a difference between SSA and pharmacy at the same 7.5 09:26
- eight_mm — the long half life flattens the trough more than people expect, i never felt a day seven dip, i could be wrong 09:30
- noct.titrate — STEP 1 ran to 68 weeks. thats the one everyone half remembers 10:06
- eight_mm — changed my mind on the four week rule, i think it depends entirely on how the current dose feels 11:01
- eight_mm — 8 months at 2.4 and the honest summary is diminishing returns after the first half 11:59
half life is about a week so youre roughly four to five weeks to steady state on any new dose, happy to be corrected
plateaus move
did anybody find a difference between SSA and pharmacy at the same 7.5
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgwent too fast once
[edited]the long half life flattens the trough more than people expect, i never felt a day seven dip, i could be wrong
[edited]👀17
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
i held at 10 for 4 months and it was the best decision i made
does moving my dose day by two days matter with a seven day half life
follow up $120 a month for compounded against what brand costs locally is why most people here use vials
thats STEP 1
is 2.4 the top or do people go past it
i stayed on 1.7 for 16 months and never went to 2.4, appetite was already where i needed it
my dose day drifted from friday to sunday, does that reset anything
how did people handle the jump from 1 to 1.7
anyone gone from 10 straight to 5 or is that too big a jump
give it four weeks
held there too
whats the actual licensed ceiling, i keep seeing different numbers
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
STEP 1 ran to 68 weeks. thats the one everyone half remembers
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changed my mind on the four week rule, i think it depends entirely on how the current dose feels
😂4💀1
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
right so held at 12 and lost 50lb over 10 months, slower than the trials and fine by me
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
does anyone actually run a five week step instead of four
8 months at 2.4 and the honest summary is diminishing returns after the first half
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compounded and brand felt the same to me at 2.4, which is one person and nothing more
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if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, i think
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
STEP is several trials, so saying STEP said x is usually wrong without a number after it
did anyone titrate slower than four weeks a step and how did that go
SELECT wasnt weight
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the plateau hit me at 34 weeks and moved again about a month later without a dose change, i could be wrong
same dose day
does the licensed ceiling for weight differ from the diabetes one