#semaglutide 2025-01-26

does moving my dose day by two days matter with a seven day half life

my Janoshik report on the TFC vial came back 98.6 against a certificate saying 96.8

does the seven day half life mean the last two days are weaker

sorry to jump in i dont think the plateau is a dose problem most of the time, but i cant prove that

did the STEP 4 withdrawal arm show what i think it showed

while im here vial units and pen clicks are different systems, mixing the two is how people end up wrong

SELECT wasnt weight

held there too

going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution, thats one data point

i stayed on 1.7 for 25 months and never went to 2.4, appetite was already where i needed it

compounded and brand felt the same to me at 1, which is one person and nothing more

went too fast once

give it four weeks

slower worked better

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, happy to be corrected

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

back after 17 months off, do i restart at 0.25 or somewhere higher

is 2.4 the top or do people go past it

how did people handle the jump from 1 to 1.7

FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure

changed my mind on the four week rule, i think it depends entirely on how the current dose feels

restarted after 13 months off at a low dose and the nausea arrived exactly like the first time, ymmv

not the same trial

coming back to this moving my dose day by a day or two never did anything noticeable for me

3 months at 2.4 and the honest summary is diminishing returns after the first half

held at 2.5 and lost 12lb over 4 months, slower than the trials and fine by me

my 30 vial in 1.5ml gives 5mg/ml so 2.4 lands on 5 units, thats why i picked that volume

STEP 1 ran to 68 weeks. thats the one everyone half remembers

vials not pens here

the appetite effect faded for me around 22 months and going up fixed it for a while

follow up SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

Purity check: no report on file for lot C-4402. Nothing logged either way.

im 16 months in at 2 and the appetite effect faded, is that a thing

i held at 0.5 for 7 months and it was the best decision i made, someone check my working

im at 5 and stuck, did anyone break a plateau without going up
changed my mind on the four week rule, i think it depends entirely on how the current dose feels

what did SELECT actually measure, i see it quoted for everything

vials not pens here

five week steps worked better for me than four, purely on how the second week felt

anyone compared their 10 vial dosing against the pen increments