if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
#semaglutide 2024-11-11
Monday14 messages3 participantstimes are UTC
Highlights from this day
- secretagogue_sy — STEP is several trials, so saying STEP said x is usually wrong without a number after it, happy to be corrected 23:27
- triple_ag_tom — the long half life flattens the trough more than people expect, i never felt a day seven dip 23:30
- VialBot — Recon calculator: 15mg in 1ml = 8mg/ml. 23:46
- secretagogue_sy — unrelated but steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 23:54
steady state takes weeks
*week 22 not week 2
STEP is several trials, so saying STEP said x is usually wrong without a number after it, happy to be corrected
the long half life flattens the trough more than people expect, i never felt a day seven dip
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
£185 a month for compounded against what brand costs locally is why most people here use vials
how long till steady state, ive read the half life is about a week
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
back after 23 months off, do i restart at 0.25 or somewhere higher
Recon calculator: 15mg in 1ml = 8mg/ml.
was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up
unrelated but steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
thats STEP 1