was SURMOUNT-OSA the one that ran to 68 weeks or am i mixing them up
#semaglutide 2024-07-12
Friday31 messages8 participantstimes are UTC
Highlights from this day
plateaus move
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
give it four weeks
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did anyone hold at 0.25 longer than four weeks before going up
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
held there too
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
follow up i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
anyone gone from 1 straight to 2.5 or is that too big a jump
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does the seven day half life mean the last two days are weaker
Assay note: QSC lot A-2418 reported at 98.1% of label content.
while im here STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
the plateau hit me at 33 weeks and moved again about a month later without a dose change, someone check my working
does the licensed ceiling for weight differ from the diabetes one
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£55 a month for compounded against what brand costs locally is why most people here use vials, i could be wrong
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
my dose day drifted from friday to sunday, does that reset anything
half life is about a week so youre roughly four to five weeks to steady state on any new dose
follow up my 30 vial in 1ml gives 4mg/ml so 2 lands on 10 units, thats why i picked that volume
[edited]went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
five week steps worked better for me than four, purely on how the second week felt
medutest-report-b-0114.pdf
3 pages · 125 KB · not retained in the public archive
my Medutest report on the QST vial came back 96.8 against a certificate saying 98.6
back after 22 months off, do i restart at 0.25 or somewhere higher
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slightly off topic but im 3 months in at 12 and the appetite effect faded, is that a thing
vials not pens here
STEP is several trials, so saying STEP said x is usually wrong without a number after it, take that with a pinch of salt
what did SELECT actually measure, i see it quoted for everything
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steady state takes weeks
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thats STEP 1
*that should say weekly
slower worked better