mine faded too
#semaglutide 2024-07-07
Sunday30 messages7 participantstimes are UTC
Highlights from this day
- noct.titrate — 16 months at 2.4 and the honest summary is diminishing returns after the first half 14:44
- mg_per_ml — does the seven day half life mean the last two days are weaker 15:45
- rotate_the_site — STEP is several trials, so saying STEP said x is usually wrong without a number after it 15:59
- typosquat_tay — my PeptideMeter report on the GGPeps vial came back 99 against a certificate saying 99.2 16:15
im 18 months in at 5 and the appetite effect faded, is that a thing
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
quick one STEP 1 ran to 68 weeks. thats the one everyone half remembers
compounded and brand felt the same to me at 1.7, which is one person and nothing more
i dont think the plateau is a dose problem most of the time, but i cant prove that
[edited]held there too
is the plateau at 15 weeks normal or am i doing something wrong
five week steps worked better for me than four, purely on how the second week felt
vials not pens here
genuine question steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
did anybody find a difference between SSA and pharmacy at the same 2.5
26 months at 2.4 and the honest summary is diminishing returns after the first half
SELECT wasnt weight
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
16 months at 2.4 and the honest summary is diminishing returns after the first half
peptidemeter-summary-g-0641.pdf
2 pages · 520 KB · not retained in the public archive
moving my dose day by a day or two never did anything noticeable for me
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plateaus move
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how many weeks before you noticed anything at 15
the long half life flattens the trough more than people expect, i never felt a day seven dip
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did the STEP 4 withdrawal arm show what i think it showed
does the seven day half life mean the last two days are weaker
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vial units and pen clicks are different systems, mixing the two is how people end up wrong, still working it out
STEP is several trials, so saying STEP said x is usually wrong without a number after it
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mgmy PeptideMeter report on the GGPeps vial came back 99 against a certificate saying 99.2
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
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i held at 2.4 for 2 months and it was the best decision i made
slower worked better
my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down