my plateau was the scale stopping while appetite stayed suppressed, which is a different problem, ymmv
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#semaglutide 2024-05-07
Tuesday23 messages6 participantstimes are UTC
Highlights from this day
- a1c_lag — the long half life flattens the trough more than people expect, i never felt a day seven dip 10:45
- apob_over_ldl — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 10:58
- lot_number_lou — went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down 11:27
SELECT wasnt weight
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
is the plateau at 17 weeks normal or am i doing something wrong
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seven days ish
held at 12 and lost 9lb over 4 months, slower than the trials and fine by me
€38 a month for compounded against what brand costs locally is why most people here use vials
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
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vial units and pen clicks are different systems, mixing the two is how people end up wrong
sorry to jump in i dont think the plateau is a dose problem most of the time, but i cant prove that
the long half life flattens the trough more than people expect, i never felt a day seven dip
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the plateau hit me at 28 weeks and moved again about a month later without a dose change
quick one i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
slightly off topic but how many weeks before you noticed anything at 0.5
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
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my VendorInvestigate report on the BCH vial came back 99.2 against a certificate saying 98.1
same dose day
give it four weeks
held there too
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
five week steps worked better for me than four, purely on how the second week felt
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |