the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
#semaglutide 2024-03-10
Sunday34 messages10 participantstimes are UTC
Highlights from this day
- vialkeeper — i dont think the plateau is a dose problem most of the time, but i cant prove that 13:35
- VialBot — New independent result logged — SWB, lot E-2205, purity 98.1% (Janoshik). 15:18
- swirl_not_shake — how many weeks before you noticed anything at 15 16:16
- swirl_not_shake — right so did anybody find a difference between SGN and pharmacy at the same 12 restarted after 26 months off at a low dose and the nausea arrived exactly like the… 16:18
- vialkeeper — unrelated but im 11 months in at 2 and the appetite effect faded, is that a thing 16:19
ok so €185 a month for compounded against what brand costs locally is why most people here use vials
is the plateau usually appetite coming back or just the scale stopping
i dont think the plateau is a dose problem most of the time, but i cant prove that
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my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
thats STEP 1
half life is about a week so youre roughly four to five weeks to steady state on any new dose
held at 0.5 and lost 68lb over 4 months, slower than the trials and fine by me
the appetite effect faded for me around 15 months and going up fixed it for a while, thats just me
dose day is sunday for me only because thats when i remember, not because sunday matters
does the seven day half life mean the last two days are weaker
*PeptideMeter not the other one
2.4 is the ceiling
my PeptideMeter report on the QSC vial came back 99.4 against a certificate saying 98.1
quick one going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution, we shall see
the plateau hit me at 23 weeks and moved again about a month later without a dose change
genuine question i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication, ask me again in a month
five week steps worked better for me than four, purely on how the second week felt
New independent result logged — SWB, lot E-2205, purity 98.1% (Janoshik).
while im here if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
five week steps worked better for me than four, purely on how the second week felt
does moving my dose day by two days matter with a seven day half life
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
did anyone hold at 5 longer than four weeks before going up
does the licensed ceiling for weight differ from the diabetes one
vials not pens here
ok so anyone compared their 4 vial dosing against the pen increments
im at 2 and stuck, did anyone break a plateau without going up
did anyone titrate slower than four weeks a step and how did that go
12 months at 2.4 and the honest summary is diminishing returns after the first half
seven days ish
how many weeks before you noticed anything at 15
[edited]right so did anybody find a difference between SGN and pharmacy at the same 12
restarted after 26 months off at a low dose and the nausea arrived exactly like the first time
unrelated but im 11 months in at 2 and the appetite effect faded, is that a thing
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