not the same trial
#semaglutide 2024-02-23
Friday29 messages8 participantstimes are UTC
Highlights from this day
- mg_per_ml — slightly off topic but STEP 1 ran to 68 weeks. thats the one everyone half remembers 13:57
- mg_per_ml — brand vs compounded, is there a difference people can actually feel 14:24
- week_three_wall — STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping 16:22
- LC_MS_Lena — i stayed on 1.7 for 9 months and never went to 2.4, appetite was already where i needed it 17:14
- VialBot — Batch lookup F-1330: 5 independent reports on file, earliest 2024-01-01. 17:29
how long did the first 13kg take for people at the low doses
is 2.4 the top or do people go past it
slightly off topic but STEP 1 ran to 68 weeks. thats the one everyone half remembers
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does moving my dose day by two days matter with a seven day half life
brand vs compounded, is there a difference people can actually feel
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went too fast once
vials not pens here
sorry to jump in i dont think the plateau is a dose problem most of the time, but i cant prove that
is there a reason to hold at 1.7 rather than going to 2.4
vial units and pen clicks are different systems, mixing the two is how people end up wrong
was SURPASS-2 the one that ran to 68 weeks or am i mixing them up
for the archive does the seven day half life mean the last two days are weaker
the long half life flattens the trough more than people expect, i never felt a day seven dip
slightly off topic but 10 months at 2.4 and the honest summary is diminishing returns after the first half
held at 1 and lost 76lb over 8 months, slower than the trials and fine by me
thats STEP 1
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
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same dose day
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the plateau hit me at 23 weeks and moved again about a month later without a dose change, someone check my working
is the plateau usually appetite coming back or just the scale stopping
[edited]my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
half life is about a week so youre roughly four to five weeks to steady state on any new dose
i stayed on 1.7 for 9 months and never went to 2.4, appetite was already where i needed it
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im at 5 and stuck, did anyone break a plateau without going up
2.4 is the ceiling
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held there too
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did anyone hold at 1.7 longer than four weeks before going up
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Batch lookup F-1330: 5 independent reports on file, earliest 2024-01-01.