no long term data
#retatrutide 2026-06-25
Thursday29 messages9 participantstimes are UTC
Highlights from this day
- residual_solvent — Janoshik came back 99.4 on one lot and 99.2 on the next from the same SSA, both fine 16:08
- cold_start_cy — appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point no idea whether the heart rate settles for everyone, mine did and one… 17:16
- cold_start_cy — anyone stayed at 2.4 for months rather than climbing 17:44
- bea_reconstitutes — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 18:49
- bea_reconstitutes — how long before people saw the first change at 7.5 18:51
GI was about the same as tirzepatide for me, the difference was how fast it arrived
glucagon is the new bit
Janoshik came back 99.4 on one lot and 99.2 on the next from the same SSA, both fine
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
On this day 3 years ago this channel logged 50 messages.
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
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phase 2 only
residual_solventtriple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long…
held at 0.25 for 13 months and it never plateaued for me, which i cant explain, happy to be corrected
appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point
no idea whether the heart rate settles for everyone, mine did and one log isnt data
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)does the energy expenditure claim show up as anything you can feel
back after 6 months, has anything actually been published since
anyone stayed at 2.4 for months rather than climbing
transit-times.csv
109 rows · not retained in the public archive
im at 2.5 and the appetite effect is stronger than i expected, normal
stepping in 0.5 increments instead of doubling is the only thing i would change if i started again
coming back to this did the phase 2 plateau or was it still moving at the end
*Janoshik not the other one
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
*that should say weekly
the heart rate thing is real enough that i mention it whenever someone asks about starting
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
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how long before people saw the first change at 7.5
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)mine went up too
slightly off topic but the half life supports weekly dosing and thats what ive done from the start
nobody should read my log as a plan, im recording what i did and thats all it is
i log resting heart rate every morning because of this and its the one number i actually watch
reconstituted the 15 vial to 10mg/ml specifically so i could take 1.7 without measuring crumbs