#retatrutide 2026-04-02

anyone logging resting heart rate on this

anyone compared their Janoshik purity across two different KP lots

nobody should read my log as a plan, im recording what i did and thats all it is, ymmv

is the phase 2 dosing anywhere near what people here run

lost 11kg over 13 months at doses well under what the trials used

the honest position is this has less human evidence behind it than anything else discussed here

low and slow

people insist on small steps because the side effects arrive faster than on the other two

no long term data

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

back after 25 months, has anything actually been published since

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

Recon calculator: 5mg in 1.5ml = 10mg/ml.

came off at 32 weeks because my resting rate stayed elevated and i didnt like it

is the GI worse than tirzepatide or about the same

did anyone come off because of the heart rate

does the glucagon arm explain the heart rate or is that unrelated

stopped for 22 months and restarted at half my old dose, the ramp was easier second time

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

i said 2 months ago that my heart rate had settled and it has stayed settled since

how slow is low and slow here, four weeks a step or longer

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

whats the half life like, is it weekly the same way

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

does the energy expenditure claim show up as anything you can feel

Medutest came back 99.4 on one lot and 98.1 on the next from the same FGP, both fine, i have it written down somewhere

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

reconstituted the 2 vial to 8mg/ml specifically so i could take 12 without measuring crumbs

research use only

genuine question whats a sensible starting point, im seeing everything from 0.5 to 2

im at 5 and the appetite effect is stronger than i expected, normal

watching my heart rate

my resting rate went up 9 bpm in the first month and came back most of the way by month 1

cant feel it honestly

i log resting heart rate every morning because of this and its the one number i actually watch, not advice obviously

anyone reconstituting 20 vials to 2.5 so the steps come out smaller

logging rhr daily

is there any long term safety data at all or is it phase 2 and hope

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

phase 2 only

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

ok so stepping in 1.7 increments instead of doubling is the only thing i would change if i started again

smaller steps here

sat at 0.5 for 3 months rather than climbing and it kept working, so i never went up

the heart rate thing is real enough that i mention it whenever someone asks about starting

anyone gone above 1 and what changed
reconstituted the 20 vial to 8mg/ml specifically so i could take 0.25 without measuring crumbs

mine went up too

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

anyone tracking blood pressure alongside the heart rate