coming back to this how long before people saw the first change at 0.5
#retatrutide 2026-03-22
Sunday35 messages8 participantstimes are UTC
Highlights from this day
- steady_state_sue — nobody should read my log as a plan, im recording what i did and thats all it is 22:42
- VialBot — Assay note: QST lot B-0114 reported at 97.4% of label content. 23:21
- pharmac_pen — for the archive held at 7.5 for 15 months and it never plateaued for me, which i cant explain, n of 1 obviously 23:28
nobody should read my log as a plan, im recording what i did and thats all it is
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logging rhr daily
my resting rate went up 9 bpm in the first month and came back most of the way by month 5
the half life supports weekly dosing and thats what ive done from the start
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
[edited]blood pressure stayed flat for me while heart rate moved, which i didnt expect
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
held mine ages
triple agonist yeah
smaller steps here
why does everyone insist on smaller steps here than on the other two
glucagon is the new bit
my resting heart rate is up about 6 bpm, did that settle for anyone
Janoshik came back 96.8 on one lot and 98.6 on the next from the same CPC, both fine
back after 12 months, has anything actually been published since
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, happy to be corrected
update on the earlier thing research use only is on every vial and i treat it as exactly that, nobody here is prescribing
right so the honest position is this has less human evidence behind it than anything else discussed here
no idea whether the heart rate settles for everyone, mine did and one log isnt data
research use only
i said 5 months ago that my heart rate had settled and it has stayed settled since
sorry to jump in energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
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Assay note: QST lot B-0114 reported at 97.4% of label content.
quick one buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
for the archive held at 7.5 for 15 months and it never plateaued for me, which i cant explain, n of 1 obviously
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i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, n of 1 obviously
lost 21kg over 11 months at doses well under what the trials used
appetite suppression at 10 was stronger than my tirzepatide experience at a comparable point
phase 2 only
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reconstituted the 15 vial to 2mg/ml specifically so i could take 0.25 without measuring crumbs
the purity spread across lots worries me more than the molecule does
low and slow
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mine went up too
unrelated but people insist on small steps because the side effects arrive faster than on the other two, anyway