anyone compared their VendorInvestigate purity across two different SGN lots
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#retatrutide 2025-11-16
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buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely, happy to be corrected
anyone logging resting heart rate on this
came off at 7 weeks because my resting rate stayed elevated and i didnt like it
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)nobody should read my log as a plan, im recording what i did and thats all it is
did the phase 2 result actually come in higher than the tirzepatide numbers
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people insist on small steps because the side effects arrive faster than on the other two
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VendorInvestigate came back 98.6 on one lot and 97.4 on the next from the same HJ, both fine
anyone gone above 1.7 and what changed
did anyone come off because of the heart rate
does the glucagon arm explain the heart rate or is that unrelated
*that should say weekly
does the energy expenditure claim show up as anything you can feel
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phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
the half life supports weekly dosing and thats what ive done from the start
research use only
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whats a sensible starting point, im seeing everything from 0.5 to 2
follow up how slow is low and slow here, four weeks a step or longer
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blood pressure stayed flat for me while heart rate moved, which i didnt expect, for what its worth
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
lost 14kg over 17 months at doses well under what the trials used
how do people square the research use only framing with logging their own use
smaller steps here
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is TRIUMPH the phase 3 programme
cant feel it honestly
mine went up too
TRIUMPH is phase 3
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energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
transit-times.csv
499 rows · not retained in the public archive
ok so reconstituted the 5 vial to 10mg/ml specifically so i could take 1.7 without measuring crumbs, i think
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
sat at 15 for 9 months rather than climbing and it kept working, so i never went up
update on the earlier thing the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
the heart rate thing is real enough that i mention it whenever someone asks about starting
no idea whether the heart rate settles for everyone, mine did and one log isnt data
glucagon is the new bit
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appetite suppression at 15 was stronger than my tirzepatide experience at a comparable point
[edited]settled by month three
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
anyone stayed at 7.5 for months rather than climbing
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
stepping in 1.7 increments instead of doubling is the only thing i would change if i started again
im at 2 and the appetite effect is stronger than i expected, normal
follow up my resting rate went up 3 bpm in the first month and came back most of the way by month 21
right so my resting heart rate is up about 5 bpm, did that settle for anyone
phase 2 only
unrelated but stopped for 8 months and restarted at half my old dose, the ramp was easier second time
no idea whether the heart rate settles for everyone, mine did and one log isnt data
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
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i said 2 months ago that my heart rate had settled and it has stayed settled since
slightly off topic but i log resting heart rate every morning because of this and its the one number i actually watch
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
no long term data
the purity spread across lots worries me more than the molecule does
people insist on small steps because the side effects arrive faster than on the other two
sorry to jump in how long before people saw the first change at 12
held mine ages
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the honest position is this has less human evidence behind it than anything else discussed here
whats the half life like, is it weekly the same way
anyone tracking blood pressure alongside the heart rate