#retatrutide 2025-11-11

Tuesday16 messages5 participantstimes are UTC

Highlights from this day

logrotate — ok so the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, still working it out 23:25
knees_first — nobody should read my log as a plan, im recording what i did and thats all it is 23:28
fridge_six_two — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 23:29

watching my heart rate

settled by month three

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

glucagon is the new bit

ok so the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, still working it out

janoshik-a-2418.pdf

2 pages · 681 KB · not retained in the public archive

nobody should read my log as a plan, im recording what i did and thats all it is

🤝3

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

does the glucagon arm explain the heart rate or is that unrelated

GI was about the same as tirzepatide for me, the difference was how fast it arrived

logging rhr daily

blood pressure stayed flat for me while heart rate moved, which i didnt expect

triple agonist yeah

phase 2 only

TRIUMPH is phase 3

🧊1

i log resting heart rate every morning because of this and its the one number i actually watch

whats the half life like, is it weekly the same way