why does everyone insist on smaller steps here than on the other two
#retatrutide 2025-10-12
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the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
whats a sensible starting point, im seeing everything from 0.5 to 2
im at 12 and the appetite effect is stronger than i expected, normal
people insist on small steps because the side effects arrive faster than on the other two
anyone logging resting heart rate on this
settled by month three
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mine went up too
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
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the purity spread across lots worries me more than the molecule does
for the archive buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
quick one TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
stopped for 24 months and restarted at half my old dose, the ramp was easier second time
my resting rate went up 7 bpm in the first month and came back most of the way by month 6
is the phase 2 dosing anywhere near what people here run
reconstituted the 30 vial to 8mg/ml specifically so i could take 0.5 without measuring crumbs
while im here i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
held mine ages
no long term data
Reminder for amsterdam_aliquot: dose day is today. Set 8 days ago.
TRIUMPH is phase 3
held at 1.7 for 23 months and it never plateaued for me, which i cant explain
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
i said 7 months ago that my heart rate had settled and it has stayed settled since
anyone stayed at 2.5 for months rather than climbing
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
how long before people saw the first change at 12
back after 5 months, has anything actually been published since
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
Medutest came back 96.8 on one lot and 97.4 on the next from the same GL Biochem, both fine
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anyone compared their PeptideMeter purity across two different GL Biochem lots
phase 2 only
[edited]low and slow
research use only
no idea whether the heart rate settles for everyone, mine did and one log isnt data
did the phase 2 plateau or was it still moving at the end
smaller steps here
watching my heart rate
glucagon is the new bit
triple agonist yeah
follow up GI was about the same as tirzepatide for me, the difference was how fast it arrived, we shall see
cant feel it honestly
stopped for 6 months and restarted at half my old dose, the ramp was easier second time
how slow is low and slow here, four weeks a step or longer
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research use only is on every vial and i treat it as exactly that, nobody here is prescribing, i have it written down somewhere
is there any long term safety data at all or is it phase 2 and hope