phase 2 only
#retatrutide 2025-10-02
- mira_pins — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 13:50
- mira_pins — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 14:17
- mira_pins — anyone reconstituting 2 vials to 2.5 so the steps come out smaller 14:54
- reta_resting_hr — Medutest came back 98.6 on one lot and 97.4 on the next from the same SWB, both fine 16:13
no long term data
did the phase 2 result actually come in higher than the tirzepatide numbers
nobody should read my log as a plan, im recording what i did and thats all it is, someone check my working
does the glucagon arm explain the heart rate or is that unrelated
GI was about the same as tirzepatide for me, the difference was how fast it arrived
quick one is there any long term safety data at all or is it phase 2 and hope
the honest position is this has less human evidence behind it than anything else discussed here, n of 1 obviously
the purity spread across lots worries me more than the molecule does
quick one whats the half life like, is it weekly the same way
im at 5 and the appetite effect is stronger than i expected, normal
Reminder set. I will post here in 2 days.
smaller steps here
anyone gone above 0.25 and what changed
settled by month three
sorry to jump in held at 12 for 19 months and it never plateaued for me, which i cant explain
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
cant feel it honestly
came off at 29 weeks because my resting rate stayed elevated and i didnt like it
lost 17kg over 5 months at doses well under what the trials used, ill dig out the number
follow up is the GI worse than tirzepatide or about the same
[edited]whats a sensible starting point, im seeing everything from 0.5 to 2
TRIUMPH is phase 3
is TRIUMPH the phase 3 programme
mine went up too
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
my resting rate went up 2 bpm in the first month and came back most of the way by month 18, i think
i log resting heart rate every morning because of this and its the one number i actually watch
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
anyone reconstituting 2 vials to 2.5 so the steps come out smaller
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
ok so appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point
i said 6 months ago that my heart rate had settled and it has stayed settled since
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
my resting heart rate is up about 7 bpm, did that settle for anyone
watching my heart rate
did anyone come off because of the heart rate
research use only
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
reconstituted the 2 vial to 10mg/ml specifically so i could take 0.25 without measuring crumbs
why does everyone insist on smaller steps here than on the other two
stepping in 15 increments instead of doubling is the only thing i would change if i started again
Medutest came back 98.6 on one lot and 97.4 on the next from the same SWB, both fine