#retatrutide 2025-07-28

Monday20 messages6 participantstimes are UTC

Highlights from this day

belfast_bac — the half life supports weekly dosing and thats what ive done from the start 17:47
bac_water_bill — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 20:43
fibre_first — how do people square the research use only framing with logging their own use 21:24

came off at 4 weeks because my resting rate stayed elevated and i didnt like it

the half life supports weekly dosing and thats what ive done from the start

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

📉2

sat at 10 for 5 months rather than climbing and it kept working, so i never went up

mine went up too

GI was about the same as tirzepatide for me, the difference was how fast it arrived

watching my heart rate

anyone logging resting heart rate on this

how long before people saw the first change at 15

logging rhr daily

reconstituted the 20 vial to 4mg/ml specifically so i could take 2 without measuring crumbs

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

the purity spread across lots worries me more than the molecule does

is TRIUMPH the phase 3 programme

slightly off topic but energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, thats one data point

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

📈2🎉1

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

⚠️6

quick one low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

is the GI worse than tirzepatide or about the same

how do people square the research use only framing with logging their own use

👀9💀7