Reminder for first_and_last_four: dose day is today. Set 4 days ago.
#retatrutide 2025-06-26
Thursday38 messages9 participantstimes are UTC
Highlights from this day
- courier_vs_post — anyone reconstituting 30 vials to 4 so the steps come out smaller nobody should read my log as a plan, im recording what i did and thats all it is 19:23
- osaka_assay — the half life supports weekly dosing and thats what ive done from the start, happy to be corrected 19:54
- courier_vs_post — quick one nobody should read my log as a plan, im recording what i did and thats all it is 20:19
- tail_factor — GI was about the same as tirzepatide for me, the difference was how fast it arrived i said 7 months ago that my heart rate had settled and it has stayed settled since 20:51
- sgp_subq — update on the earlier thing did anyone come off because of the heart rate 21:05
logging rhr daily
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anyone stayed at 0.5 for months rather than climbing
appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point
held mine ages
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
stepping in 2 increments instead of doubling is the only thing i would change if i started again
mine went up too
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
cant feel it honestly
Batch lookup SG-1177: 6 independent reports on file, earliest 2025-01-28.
TRIUMPH is phase 3
anyone reconstituting 30 vials to 4 so the steps come out smaller
nobody should read my log as a plan, im recording what i did and thats all it is
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TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
slightly off topic but energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
no long term data
is TRIUMPH the phase 3 programme
reconstituted the 2 vial to 8mg/ml specifically so i could take 0.25 without measuring crumbs
nobody should read my log as a plan, im recording what i did and thats all it is
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triple agonist meaning GLP-1, GIP and glucagon, have i got that right
the half life supports weekly dosing and thats what ive done from the start, happy to be corrected
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i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
quick one nobody should read my log as a plan, im recording what i did and thats all it is
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watching my heart rate
[edited]research use only is on every vial and i treat it as exactly that, nobody here is prescribing, i could be wrong
GI was about the same as tirzepatide for me, the difference was how fast it arrived
i said 7 months ago that my heart rate had settled and it has stayed settled since
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settled by month three
is the glucagon arm what people mean by the energy expenditure thing
update on the earlier thing did anyone come off because of the heart rate
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Medutest came back 99.2 on one lot and 99.4 on the next from the same GL Biochem, both fine
i said 9 months ago that my heart rate had settled and it has stayed settled since
phase 2 only
lost 29kg over 23 months at doses well under what the trials used
stopped for 26 months and restarted at half my old dose, the ramp was easier second time, someone check my working
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
is the phase 2 dosing anywhere near what people here run
genuine question phase 2 was still trending at the end which is why the phase 3 readout matters more than usual