the honest position is this has less human evidence behind it than anything else discussed here
#retatrutide 2025-06-21
Saturday22 messages5 participantstimes are UTC
Highlights from this day
- meniscus_mel — for the archive anyone tracking blood pressure alongside the heart rate 14:14
- ema_vs_national — Medutest came back 97.4 on one lot and 96.8 on the next from the same GL Biochem, both fine, take that with a pinch of salt 14:46
- meniscus_mel — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual held at 1 for 24 months and it never plateaued for me, which i cant… 16:36
settled by month three
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for the archive anyone tracking blood pressure alongside the heart rate
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triple agonist yeah
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
cant feel it honestly
[edited]Medutest came back 97.4 on one lot and 96.8 on the next from the same GL Biochem, both fine, take that with a pinch of salt
TRIUMPH is phase 3
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the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
came off at 18 weeks because my resting rate stayed elevated and i didnt like it
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
mine went up too
phase 2 only
watching my heart rate
smaller steps here
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
ok so why does everyone insist on smaller steps here than on the other two
[edited]phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
held at 1 for 24 months and it never plateaued for me, which i cant explain
i log resting heart rate every morning because of this and its the one number i actually watch
is the GI worse than tirzepatide or about the same
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, n of 1 obviously
does the glucagon arm explain the heart rate or is that unrelated