vialroom

#retatrutide 2025-03-25

Tuesday22 messages6 participantstimes are UTC
Highlights from this day
  • see_a_clinician — sat at 2 for 6 months rather than climbing and it kept working, so i never went up 22:18
  • VialBot — On this day 5 years ago this channel logged 123 messages. 23:02
  • dexa_or_bia — unrelated but phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 23:08

held mine ages

glucagon is the new bit

BS

im at 1 and the appetite effect is stronger than i expected, normal

DO

GI was about the same as tirzepatide for me, the difference was how fast it arrived

BS

held at 5 for 20 months and it never plateaued for me, which i cant explain

SA

sat at 2 for 6 months rather than climbing and it kept working, so i never went up

17
SS

the heart rate thing is real enough that i mention it whenever someone asks about starting

DO

no long term data

weights-monthly.csv
323 rows · not retained in the public archive

watching my heart rate

🤝4❤️3👍9
SS

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

SS

research use only

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
DO

slightly off topic but i log resting heart rate every morning because of this and its the one number i actually watch

SS

reconstituted the 10 vial to 2.5mg/ml specifically so i could take 0.5 without measuring crumbs

VB

On this day 5 years ago this channel logged 123 messages.

DO

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

unrelated but phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

💀4

appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point, from memory

PP

follow up the half life supports weekly dosing and thats what ive done from the start