unrelated but the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
#retatrutide 2025-02-23
Sunday39 messages6 participantstimes are UTC
Highlights from this day
- gall_bladder_gav — TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule 20:50
- half_life_hal — stepping in 7.5 increments instead of doubling is the only thing i would change if i started again 21:05
- reta_resting_hr — nobody should read my log as a plan, im recording what i did and thats all it is 21:48
smaller steps here
genuine question energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
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anyone reconstituting 2 vials to 2.5 so the steps come out smaller
research use only
TRIUMPH is phase 3
held at 2.5 for 21 months and it never plateaued for me, which i cant explain
is the GI worse than tirzepatide or about the same
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did the phase 2 result actually come in higher than the tirzepatide numbers
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
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ok so GI was about the same as tirzepatide for me, the difference was how fast it arrived
mine went up too
triple agonist yeah
stepping in 7.5 increments instead of doubling is the only thing i would change if i started again
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reconstituted the 20 vial to 4mg/ml specifically so i could take 1 without measuring crumbs, ymmv
while im here buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
people insist on small steps because the side effects arrive faster than on the other two
why does everyone insist on smaller steps here than on the other two
is there any long term safety data at all or is it phase 2 and hope
sat at 5 for 8 months rather than climbing and it kept working, so i never went up
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
is the glucagon arm what people mean by the energy expenditure thing
phase 2 only
anyone tracking blood pressure alongside the heart rate
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
blood pressure stayed flat for me while heart rate moved, which i didnt expect
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VendorInvestigate came back 99.4 on one lot and 96.8 on the next from the same FGP, both fine
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
medutest-report-h-2814.pdf
3 pages · 169 KB · not retained in the public archive
anyone compared their PeptideMeter purity across two different QST lots
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how slow is low and slow here, four weeks a step or longer
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
watching my heart rate
i log resting heart rate every morning because of this and its the one number i actually watch
the heart rate thing is real enough that i mention it whenever someone asks about starting
low and slow
nobody should read my log as a plan, im recording what i did and thats all it is
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my resting heart rate is up about 7 bpm, did that settle for anyone
logging rhr daily
the honest position is this has less human evidence behind it than anything else discussed here
week_three_wallreconstituted the 20 vial to 4mg/ml specifically so i could take 1 without measuring…
sorry to jump in back after 7 months, has anything actually been published since
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i said 2 months ago that my heart rate had settled and it has stayed settled since