whats the half life like, is it weekly the same way
#retatrutide 2024-12-10
Tuesday39 messages10 participantstimes are UTC
Highlights from this day
- group_buy_gwen — i log resting heart rate every morning because of this and its the one number i actually watch, i think 20:50
- monoisotopic — buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely 21:14
- reta_resting_hr — i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind 21:43
- marrow.mod — is the GI worse than tirzepatide or about the same 22:37
*PeptideMeter not the other one
nobody should read my log as a plan, im recording what i did and thats all it is
how long before people saw the first change at 12
reconstituted the 15 vial to 4mg/ml specifically so i could take 0.5 without measuring crumbs
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
anyone gone above 0.25 and what changed
anyone logging resting heart rate on this
no long term data
watching my heart rate
is the glucagon arm what people mean by the energy expenditure thing
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
im at 0.25 and the appetite effect is stronger than i expected, normal
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, i think
lost 11kg over 7 months at doses well under what the trials used
unrelated but energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
no idea whether the heart rate settles for everyone, mine did and one log isnt data
i log resting heart rate every morning because of this and its the one number i actually watch, i think
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did the phase 2 plateau or was it still moving at the end
whats a sensible starting point, im seeing everything from 0.5 to 2
glucagon is the new bit
buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
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is there any long term safety data at all or is it phase 2 and hope
did anyone come off because of the heart rate
held at 12 for 22 months and it never plateaued for me, which i cant explain, happy to be corrected
smaller steps here
sat at 15 for 5 months rather than climbing and it kept working, so i never went up, still working it out
logging rhr daily
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
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sorry to jump in research use only is on every vial and i treat it as exactly that, nobody here is prescribing, happy to be corrected
is TRIUMPH the phase 3 programme
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
no idea whether the heart rate settles for everyone, mine did and one log isnt data
PeptideMeter came back 99 on one lot and 99.4 on the next from the same ERP, both fine
TRIUMPH is phase 3
is the GI worse than tirzepatide or about the same
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people insist on small steps because the side effects arrive faster than on the other two
mine went up too
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came off at 28 weeks because my resting rate stayed elevated and i didnt like it