does the energy expenditure claim show up as anything you can feel
#retatrutide 2024-09-05
- bac_water_bill — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 16:57
- taper_tess — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 17:31
- taper_tess — no idea whether the heart rate settles for everyone, mine did and one log isnt data 17:34
- taper_tess — sat at 10 for 2 months rather than climbing and it kept working, so i never went up phase 2 doses are published and theyre not far off what people here run,… 17:35
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
the heart rate thing is real enough that i mention it whenever someone asks about starting
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
watching my heart rate
is the GI worse than tirzepatide or about the same
phase 2 only
appetite suppression at 5 was stronger than my tirzepatide experience at a comparable point
genuine question there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
anyone stayed at 12 for months rather than climbing
stepping in 1.7 increments instead of doubling is the only thing i would change if i started again, ymmv
settled by month three
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
smaller steps here
logging rhr daily
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
low and slow
for the archive did the phase 2 plateau or was it still moving at the end
i log resting heart rate every morning because of this and its the one number i actually watch
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
is the glucagon arm what people mean by the energy expenditure thing
held mine ages
no idea whether the heart rate settles for everyone, mine did and one log isnt data
sat at 10 for 2 months rather than climbing and it kept working, so i never went up
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
im at 7.5 and the appetite effect is stronger than i expected, normal
sorry to jump in did the phase 2 result actually come in higher than the tirzepatide numbers