vialroom

#retatrutide 2024-05-19

Sunday24 messages8 participantstimes are UTC
Highlights from this day
  • VialBot — Inter-lab diff for lot C-4402: 99.2% vs 99%. Within expected range. 14:16
  • pinch_not_stretch — buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely 14:46
  • a1c_lag — slightly off topic but i log resting heart rate every morning because of this and its the one number i actually watch, i have it written down somewhere 15:31
  • a1c_lag — does the glucagon arm explain the heart rate or is that unrelated 15:32
  • a1c_lag — is the glucagon arm what people mean by the energy expenditure thing 15:35
NS

the honest position is this has less human evidence behind it than anything else discussed here

VB

Inter-lab diff for lot C-4402: 99.2% vs 99%. Within expected range.

BS

came off at 33 weeks because my resting rate stayed elevated and i didnt like it

anyone stayed at 0.5 for months rather than climbing

cant feel it honestly

3
U1

i said 8 months ago that my heart rate had settled and it has stayed settled since

no idea whether the heart rate settles for everyone, mine did and one log isnt data

PN

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

glucagon is the new bit

*Janoshik not the other one

smaller steps here

A1

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

A1

slightly off topic but i log resting heart rate every morning because of this and its the one number i actually watch, i have it written down somewhere

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

does the glucagon arm explain the heart rate or is that unrelated

10

is the glucagon arm what people mean by the energy expenditure thing

👀17👍4🙏17
BS

stopped for 2 months and restarted at half my old dose, the ramp was easier second time, n of 1 obviously

unrelated but the purity spread across lots worries me more than the molecule does

anyone reconstituting 20 vials to 2 so the steps come out smaller