vialroom

#reconstitution 2025-06-02

Monday41 messages8 participantstimes are UTC
Highlights from this day
  • glasgow_vial — bacteriostatic water for anything multi-use. sterile water has no preservative in it at all 14:38
  • igf_one_ivy — is there any reason not to just always use 2ml 15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it 14:39
  • igf_one_ivy — dead space in a standard insulin syringe hub is small but it is not nothing over a month 14:40
IO

i write the mg/ml on the vial with a sharpie the moment i reconstitute it

lyophilised powder is far more robust than people think. it is the solution that is fragile

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

i was wrong about this last year: it is fine to draw cold, it just stings more going in

a slightly collapsed cake is cosmetic. a puddle in the bottom is not

yep 10 units

update on the earlier thing my rule is one concentration for everything so i never have to think about it at 7am, from memory

TT

swirl dont shake

weights-monthly.csv
705 rows · not retained in the public archive

does temperature of the bac water matter at all

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy, your mileage will differ

BB

update from 20 months ago: switched to a single concentration and have not miscalculated since

WV

10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use, i have it written down somewhere

TT

i have never once regretted using a rounder number and a slightly bigger volume

TT

the meniscus thing is real. read it at eye level or you are guessing by a unit either way

gross powder mass is not net peptide. water and counterion are in that number, n of 1 obviously
lyophilised powder is far more robust than people think. it is the solution that is fragile

fridge-temps.csv
318 rows · not retained in the public archive
GV

anyone worked out a recon volume that puts 10mg on a round unit mark

bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

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IO

is there any reason not to just always use 2ml
15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it

👀18🙏6

dead space in a standard insulin syringe hub is small but it is not nothing over a month

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SC

coming back after 24 months, has the pinned recon volume advice changed

💀111

is it worth buying a 3ml syringe for the diluent or is the insulin one fine
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol

im getting bubbles in the barrel every single time, what am i doing wrong

LU

took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience

BB

do not add more bac water to an already reconstituted vial, you have lost track of the concentration

LU

30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right