vialroom

#reconstitution 2025-02-15

Saturday42 messages11 participantstimes are UTC
Highlights from this day
  • orfor_watch — give it 6 minutes at room temperature before you decide it has not dissolved 22:51
  • orfor_watch — pick the volume so your dose is a whole number of units. thats the entire trick 22:53
  • taper_tess — if the maths gives you 13.7 units, change the volume. do not try to hit 13.7 23:00
  • related_subs — how long after reconstituting before its actually dissolved 23:02
  • lipase_lore — temperature of the diluent does not matter. how fast you push it in does 23:17

one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that

i write the mg/ml on the vial with a sharpie the moment i reconstitute it

🧊2

benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically

weighing the vial before you reconstitute is the only way to catch an underfill

[edited]
MS

i keep a spare vial of bac water in the fridge purely so i never rush the maths

VB

Batch lookup B-0329: 5 independent reports on file, earliest 2024-10-23.

OW

5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose

MM

update on the earlier thing do not add more bac water to an already reconstituted vial, you have lost track of the concentration, i have it written down somewhere

OW

the meniscus thing is real. read it at eye level or you are guessing by a unit either way

i swirl for about thirty seconds and then leave it. never had one fail to dissolve
give it 3 minutes at room temperature before you decide it has not dissolved

i was wrong about this last year: it is fine to draw cold, it just stings more going in, someone check my working

pick the volume so your dose is a whole number of units. thats the entire trick

10mg vial
  + 1.0ml  -> 10.0 mg/ml   0.5mg =  5u   1mg = 10u
  + 2.0ml  ->  5.0 mg/ml   0.5mg = 10u   1mg = 20u
  + 2.5ml  ->  4.0 mg/ml   0.5mg = 12.5u (dont)
  + 5.0ml  ->  2.0 mg/ml   0.5mg = 25u   1mg = 50u
16📈5

bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

TS

my rule is one concentration for everything so i never have to think about it at 7am

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

TT

if the maths gives you 13.7 units, change the volume. do not try to hit 13.7

😂5🤝1💀1

one unit is 0.01ml

20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy

read it at eye level

a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with, i think

*VendorInvestigate not the other one

LL

temperature of the diluent does not matter. how fast you push it in does

🧪1🧊6

sorry to jump in dead space in a standard insulin syringe hub is small but it is not nothing over a month

thats the vacuum

quick one does it matter if i inject the bac water straight at the powder

[edited]

quick one the last few units are a real loss. i accept it rather than tilting the vial and drawing air

not sterile water

clear or bin it

foam is bad