round numbers
#reconstitution 2024-12-07
Saturday34 messages6 participantstimes are UTC
Highlights from this day
- electrolyte_eli — bacteriostatic water for anything multi-use. sterile water has no preservative in it at all, your mileage will differ 11:53
- residual_solvent — ok so a slightly collapsed cake is cosmetic. a puddle in the bottom is not 14:08
- residual_solvent — 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right 14:26
- electrolyte_eli — how much do i lose to dead space with a 30G pin dead space in a standard insulin syringe hub is small but it is not nothing over a month 14:48
- tenpence — the jewellery scale is a good habit but calibrate it, they drift badly swirl it. do not shake it. the foam is denatured protein and you are not getting it back 15:18
thats the vacuum
thats fine
bac water
too dilute imo
not sterile water
bacteriostatic water for anything multi-use. sterile water has no preservative in it at all, your mileage will differ
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is the meniscus reading actually a real source of error or am i overthinking
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
it should be completely clear with no floaters. cloudy means stop
dead space in a standard insulin syringe hub is small but it is not nothing over a month
clear or bin it
nope, redo it
is there any reason not to just always use 2ml
foam is bad
my vial pulled the water in on its own, is that the vacuum or did i do something
my 10mg vial weighed 11.4g on the jewellery scale, is that wrong
why does everyone say 2ml specifically and not 1ml
ok so a slightly collapsed cake is cosmetic. a puddle in the bottom is not
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30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
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whats the smallest volume you would trust yourself to measure on a u100
is it worth buying a 3ml syringe for the diluent or is the insulin one fine
sanity check my maths before i pin myself with something stupid
took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience
my rule is one concentration for everything so i never have to think about it at 7am, happy to be corrected
how much do i lose to dead space with a 30G pin
dead space in a standard insulin syringe hub is small but it is not nothing over a month
one unit is 0.01ml
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what do you do with the last 10 units when you cant draw them cleanly
the jewellery scale is a good habit but calibrate it, they drift badly
swirl it. do not shake it. the foam is denatured protein and you are not getting it back
swirl dont shake
the last few units are a real loss. i accept it rather than tilting the vial and drawing air, thats one data point
[edited]temperature of the diluent does not matter. how fast you push it in does
weigh it first
benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically