vialroom

#reconstitution 2024-11-20

Wednesday32 messages5 participantstimes are UTC
Highlights from this day
  • step_one_sian — dead space in a standard insulin syringe hub is small but it is not nothing over a month 13:24
  • split_shipment — right so is it normal for the cake to look slightly collapsed on one side 13:25
  • chlorhex — if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space 14:02

sorry to jump in anyone worked out a recon volume that puts 1.7mg on a round unit mark

do you let it come to room temp before drawing or draw it cold

SS

one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that, not advice obviously

nobody here should be telling you a dose. we can check your arithmetic, thats a different thing

one unit is 0.01ml

SO

bacteriostatic water for anything multi-use. sterile water has no preservative in it at all

SS

gross powder mass is not net peptide. water and counterion are in that number

SO

dead space in a standard insulin syringe hub is small but it is not nothing over a month

❤️11😂13
SS

right so is it normal for the cake to look slightly collapsed on one side

⚠️13📈7
CH

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space

😂51👀1

the last few units are a real loss. i accept it rather than tilting the vial and drawing air

it should be completely clear with no floaters. cloudy means stop

yep 10 units

if i add 1ml to a 2mg vial what concentration am i actually at

SS

lyophilised powder is far more robust than people think. it is the solution that is fragile

[edited]
SS

swirl it. do not shake it. the foam is denatured protein and you are not getting it back

im getting bubbles in the barrel every single time, what am i doing wrong

pick the volume so your dose is a whole number of units. thats the entire trick

SO

a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with

follow up it foamed. is it ruined