PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
#oral-glp1 2026-06-18
Thursday15 messages5 participantstimes are UTC
Highlights from this day
- pinch_not_stretch — the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them 16:33
- u100_pat — quick one back after 1 months, has anything changed on the oral side roughly one percent gets absorbed, which is why the tablet strength looks nothing like an… 17:20
- u100_pat — coffee is not plain water. i tried it for a month and my results got worse 17:59
- VialBot — Testing queue: 6 submissions open, 131 awaiting dispatch. 18:15
- pinch_not_stretch — coming back to this why is the oral dose in mg so much bigger than the injectable one 18:57
the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them
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SNAC does the work
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is the inconsistency people report about the drug or about how they take it
quick one back after 1 months, has anything changed on the oral side
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose
coffee is not plain water. i tried it for a month and my results got worse
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coming back to this the oral mg number is bigger because almost none of it gets in, thats the entire reason
lost 16kg over 22 months on oral, slower than my injectable stretch, i stuck with it anyway
Testing queue: 6 submissions open, 131 awaiting dispatch.
coming back to this why is the oral dose in mg so much bigger than the injectable one
weights-monthly.csv
258 rows · not retained in the public archive
update on the earlier thing the non peptide agents dose daily without the water ritual, thats the practical difference
PIONEER or OASIS, which one was the higher dose oral
about one percent
fasted every morning
anyone dosing oral because of a needle problem rather than preference
the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them