vialroom

#oral-glp1 2026-03-05

Thursday32 messages9 participantstimes are UTC
Highlights from this day
  • ten_of_ten — roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, your mileage will differ 11:56
  • vale_vials — sorry to jump in how strict is the 30 minute wait before food for people here 12:34
  • fake_tracking — my weekly log on oral is noisier than my injectable log ever was, same scales same mornings 13:44
  • knees_first — OASIS ran under the same sort of fasting conditions, thats not the variable between the two coffee is not plain water. i tried it for a month and my results got worse 15:35
SS

coming back to this SNAC raises the local pH and protects it long enough to cross, thats its whole job

sorry to jump in how long before the oral did anything measurable for you

nobody should copy my morning routine, but the timer is the bit i would keep

TO

anyone tracking whether their oral results line up week to week

TO

roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, your mileage will differ

VV

plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly, n of 1 obviously

VV

sorry to jump in how strict is the 30 minute wait before food for people here

🔥1

*sorry, BCH

FT

took mine with breakfast once by accident and that week was a write off

FT

my weekly log on oral is noisier than my injectable log ever was, same scales same mornings

📉7

is the absorption variability why the oral doses look so high

the oral mg number is bigger because almost none of it gets in, thats the entire reason

*PeptideMeter not the other one

TO

oral was easier on my gut than injecting at what felt like a similar effect, which surprised me

not a peptide

technique probably

MM

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted

KF

the inconsistency is mostly technique and admitting that took me about a year

went back to injecting

👀1
KF

the non peptide orals are the interesting part of this channel now, not oral semaglutide

KF

whats the bioavailability actually like, i keep seeing about one percent